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Conclusion: Although GHK-Cu and Pal-GHK are effective and relatively skin permeable, their permeability could be successfully increased using permeation enhancement methodologies
Hello Mauschen , I also visit Germany regularly , about twice a year
In fibroblast cell studies, GHK-Cu stimulated collagen synthesis at nanomolar concentrations (10 -9 M), which matters because it means effective activity at very low doses in well-formulated serums
Where results are borderline, measurement of methylmalonic acid (MMA) or holotranscobalamin (active B12) may help clarify the picture, as recommended in NICE CKS guidance on B12 and folate deficiency anaemia
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